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Patients with the rare clonidine hereditary conditions of galactose intolerance e .
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Use in children and adolescents The use and the safety of clonidine clonidine in children and adolescents has little supporting evidence in randomised controlled trials and therefore cannot be recommended for use in this population .
In particular, when clonidine is used off-label concomitantly with methylphenidate in children with clonidine ADHD, serious adverse reactions, including death, have been observed .
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